Premature ejaculation (PE) is a frequent problem many men in the world suffer from. Premature ejaculation occurs when one climaxes earlier than they would want to—sometimes within just one minute of beginning. This can be very stressful, frustrating, and even lead to relationship problems. Fortunately, medical technology has made some excellent advances, introducing a lot of useful drug treatments that can really assist men in gaining control over ejaculation and enhancing sexual pleasure. This blog looks at the best drugs for PE, what they do, their success rate, potential risks, and what you should expect when you want to get a prescription.
Now, let’s go into medications that are made especially to treat premature ejaculation.
Physicians tend to prescribe medication for premature ejaculation when behavioral treatments or lifestyle adjustments simply aren’t working. Therefore, though there may not be an FDA-approved medication for PE in most nations, there are actually several medications that were originally developed for other conditions. Individuals tend to use them off-label since they’ve been found to be effective at delaying ejaculation. The most typical classes are listed below:
- SSRIs
- Lidocaine or prilocaine sprays and creams are topical anesthetics.
- PDE5 inhibitors
- Tramadol is an opioid analgesic that’s not used as frequently anymore due to its side effects.
How These Drugs Work in the Body
SSRIs are a class of drugs that comprise dapoxetine, sertraline, paroxetine, and fluoxetine, and they primarily work as antidepressants. You see, how they delay ejaculation really is a side effect that proves beneficial for guys suffering from PE.
SSRIs increase the levels of serotonin in the brain, and it’s believed to slow down the ejaculatory reflex so that it takes longer to have an orgasm.
Dapoxetine stands alone in that it’s the only SSRI specifically meant to be used on an as-needed basis for premature ejaculation. It acts fast and doesn’t last very long, so you can administer it a couple of hours prior to engaging in intimacy.
Topical Anesthetics: Lidocaine and prilocaine creams or sprays can be applied directly on the penis to reduce nerve sensitivity.
These drugs act by desensitizing the skin, thereby lessening overstimulation and enabling men to last longer during sex.
PDE5 Inhibitors are relatively popular drugs, aren’t they? You’ve likely heard of sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra). Although primarily prescribed for erectile dysfunction, they can be prescribed off-label for premature ejaculation.
They work by increasing blood flow to the penis, which may cause improved quality of erections and, in some men, improved ability to control ejaculation.
Tramadol is an opioid-type painkiller, and interestingly enough, it also delays ejaculation as a side effect. But generally speaking, it’s reserved for use in instances where other forms of treatment of ejaculation aren’t doing the job, because it can cause dependence and there are some side effects to think about.
Let’s discuss how good the best treatments are doing and what people have to say about them.
A lot of clinical trials have indicated how well these drugs work:
- SSRIs: So, when it comes to Sertraline, research indicates that the average ejaculation time can jump from just one minute to more than 7 minutes with lower doses, and it can even reach up to 16 minutes with higher doses.
- Paroxetine is also considered the go-to SSRI for PE, with some significant results. When taken daily, it can increase intravaginal ejaculatory latency time (IELT) from below one minute to well above 4 minutes.
- So, with Dapoxetine, individuals have been able to increase their IELT from about 30 seconds to nearly 3 minutes, and the best thing is, you can take it when you need it.
- PDE5 Inhibitors: So, in 2007, they had this one that indicated sildenafil performed better than both SSRI and behavioral methods when it came to ejaculatory control and increasing sexual satisfaction.
There are studies which imply that with the use of a combination of SSRI and PDE5 inhibitor, there can be even greater outcome and satisfaction.
Topical Anesthetics:
Many men report that they feel more control from the start, but some may have less sensation, which will affect their pleasure.
Most people give good feedback, particularly when they have an idea of what to expect and have few side effects. Keep in mind, though, that everyone is different and not all men are going to notice dramatic changes.
Hi, let’s talk about some potential risks and drug interactions you should be aware of.
So, although these drugs are generally safe when taken as prescribed, there are still certain risks:
SSRIs
Certain side effects you may have include nausea, headaches, feeling sleepy, a decline in libido, and sometimes difficulty reaching orgasm, especially if taking higher doses.
Thus, in terms of drug interactions, SSRIs can interact with other antidepressants, certain pain medications, and even some herbal supplements. This will increase the risk of serotonin syndrome, which is not something to ignore.
Now, let’s discuss topical anesthetics.
There are certain risks involved, such as allergic reactions or the numbing agent being transferred to a sex partner, which might reduce their sensation as well.
PDE5 Inhibitors:
Certain side effects you may experience are headaches, flushing, runny nose, and in uncommon cases, vision changes or priapism, or erection that lasts longer than four hours.
Hi, just a quick warning regarding drug interactions: you should not take this with nitrates or some blood pressure medication because it can cause some drastic drops in blood pressure.
Tramadol:
So there are a few dangers to be aware of: you may feel sleepy, be nauseous, there’s the possibility of becoming addicted, and it can get abused.
It’s absolutely essential to discuss your full medical history and any medications you’re currently on with your doctor. This allows you to avoid any interactions and obtain the safest, most effective treatment of ejaculation for you.
So, you’re considering getting a prescription? Here’s what you can anticipate if you visit your doctor.
Getting treatment for PE can be a little scary, but physicians actually know how to deal with sexual health problems. So, here’s what you can expect:
Let’s talk about it:
Your physician will want to discuss your sexual history, how long you have been having symptoms, how severe the symptoms are, and whether there is a medical or psychological problem at work.
They may also inquire about the quality of your relationships, your level of stress, and other factors that may contribute to PE.
Let’s discuss the physical examination and the tests involved
At times, physicians will perform a physical examination or certain blood work to screen for hormonal imbalances or other health problems.
Here is the treatment plan:
If medication is the option, your physician will discuss with you the choices, what you can anticipate as benefits, and any likely side effects.
Some drugs, including dapoxetine, may be taken only when needed, whereas others, including SSRIs, should be taken every day to produce the best effects.
It’s quite standard to follow up with appointments to monitor progress and adjust the treatment of ejaculation if needed.
Living Tips and Behavior:
Physicians may recommend combining medication with some behavioral interventions or counseling to achieve the best outcomes.
In conclusion
Premature ejaculation is something that a great number of individuals go through, and there’s good news in that it can be treated.
A great number of men have discovered that drugs such as SSRIs, topical anesthetics, and PDE5 inhibitors are really effective at making them more assured and pleased with their sexual lives. These medications are effective for a great number of individuals, but there’s really no substitute for talking with a healthcare provider. They can tailor the treatment of ejaculation to you, monitor for side effects, and ensure all is well with any other medication you may be on. With the proper technique, you can certainly overcome PE, to unlock a more fulfilling intimate life.
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